SOLID STATE CHARACTERIZATION OF A NOVEL PHYSICAL INTERACTION (PARACETAMOL-CHLORPHENIRAMINE MALEATE)
نویسندگان
چکیده
منابع مشابه
Simultaneous Determination of Chlorpheniramine Maleate, Phenylephrine Hydrochloride, Paracetamol and Caffeine in Pharmaceutical Preparation by Rp-hplc
A reversed-phase High-Performance Liquid-Chromatography (RP-HPLC) method was successfully developed for the simultaneous determination of quaternary mixture consisting of chlorpheniramine maleate (CPM), phenylephrine hydrochloride (PE), paracetamol (PCM) and caffeine in pharmaceutical preparation. The method was found to be simple, sensitive and rapid. The separation of the drugs was carried ou...
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Antihistamines are commonly used to treat allergic disease, such as allergic rhinitis, urticaria, and angioedema. Although several previous reports describe hypersensitivity to antihistamines such as cetirizine and hydroxyzine, documented cases of chlorpheniramine hypersensitivity are extremely rare. Here, we report the case of a 45-year-old Korean woman who presented with urticaria after inges...
متن کاملFormulation and Evaluation of Medicated Chewing Gums of Chlorpheniramine Maleate
The aim of the present work is development and evaluation of Chlorpheniramine maleate medicated chewing gums and to study the influence of different plasticizers on physicochemical parameters and in vitro drug release profile. Chlorpheniramine maleate is used to relieve symptoms of allergy, hay fever and common cold. Prepared formulations are evaluated for thickness, hardness, weight variation,...
متن کاملValidated RP-HPLC method for simultaneous determination and quantification of chlorpheniramine maleate, paracetamol and caffeine in tablet formulation
Chlorpheniramine maleate-paracetamol-caffeine tablet formulation is one of the common over-the-counter drugs used for the treatment of cold and cough. A reversed-phase high-performance liquid-chromatography method has been successfully developed for the simultaneous determination of chlorpheniramine maleate, paracetamol and caffeine in a drug formulation. The RP-HPLC method employed a Phenomene...
متن کاملControlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis.
A double-blind clinical trial in 60 patients with perennial rhinitis was conducted to compare the efficacy and side effects of two antihistamines, terfenadine and chlorpheniramine maleate, and placebo. There was no statistically significant difference in response between active treatments and placebo. Although side effects were more frequent with chlorpheniramine this also was not statistically...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2018
ISSN: 0975-7058
DOI: 10.22159/ijap.2018v10i1.22840